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Aminopyridines
Author(s) -
Jünemann Werner,
Opgenorth HansJoachim,
Scheuermann Horst
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198003881
Subject(s) - aminopyridines , chemistry , organic chemistry
An adaptable synthesis of 4,5‐unsubstituted pyridines starts from ethyl propiolate (1) . The diols (3) can be transformed into dichlorides, which in turn afford diamines. Triamines are accessible from malonic ester and (2) , R 1 = C 6 H 5 SO 2 , via the triols (4) .