Premium
Oxidation of Isatins to Isatoic Anhydrides and 2,3‐Dioxo‐1,4‐benzoxazines
Author(s) -
Reissenweber Gernot,
Mangold Dietrich
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198002221
Subject(s) - oxidizing agent , chromium trioxide , acetic anhydride , acetic acid , chemistry , organic chemistry , chromium , catalysis
Depending upon the oxidizing agent employed, various products are obtained from isatins (1): H 2 O 2 /glacial acetic acid leads to isatoic anhydrides (2) , whereas H 2 S 2 O 8 /H 2 SO 4 furnishes 2,3‐dioxo‐1,4‐benzoxazines (3) . Compound (1) is usually oxidized to (2) with the toxic chromium trioxide.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom