Premium
Crystal Structure of 2‐Lithio‐2‐methyl‐1,3‐dithiane Tetramethylethylenediamine
Author(s) -
Amstutz René,
Seebach Dieter,
Seiler Paul,
Schweizer Bernd,
Dunitz Jack D.
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198000531
Subject(s) - tetramethylethylenediamine , steric effects , dimer , lithium (medication) , crystallography , chemistry , dithiane , molecule , crystal structure , crystal (programming language) , stereochemistry , medicinal chemistry , medicine , organic chemistry , endocrinology , computer science , programming language
Surprising structural features were revealed by an X‐ray study of the title compound (1): it crystallizes as dimer and one molecule each of the solvent TMEDA (tetramethylethylenediamine) is coordinated in spirane fashion to a Li atom. The equatorial position of the lithium is thus possibly a result of steric rather than electronic factors.