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Intramolecular Cycloadditions of Carbonyl Ylides
Author(s) -
Eberbach Wolfgang,
Brokatzky Jürgen,
Fritz Hans
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198000471
Subject(s) - intramolecular force , cycloaddition , stereoselectivity , chemistry , intramolecular reaction , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Stereoselective syntheses of heterocycles represent an important area of application of intramolecular 1,3‐dipolar cycloaddition. With the aid of model compounds (1), n = 1, 2, it is demonstrated that also carbonyl ylides such as (2) and (3) can undergo this type of reaction. Reaction of (3), n = 1, affords (4) while reaction of (2), n = 1, 2, leads to the trans ‐coupled compounds corresponding to (4) .
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