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Enzymatic Formation of Uroporphyrinogen I and III from a Substituted Bilane
Author(s) -
Kammerer Peter,
Wörner Gertrud,
Müller Gerhard
Publication year - 1979
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197907781
Subject(s) - chemistry , ring (chemistry) , isomerization , stereochemistry , enzyme , biochemistry , catalysis , organic chemistry
The “reversed ring” in uroporphyrinogen(III) (uro'gen III), the parent compound of all natural porphyrins, etc. , could arise in two different ways: (i) by isomerization of a head‐to‐tail linked bilane such as (1) on ring closure or (ii) by formation of a precursor with a “reversed” ring. Enzymatic studies now show the former route to apply.