Premium
Synthesis and Intramolecular 1,3 Cl,H Disproportionation of Ethyl 2,2‐Dichloro‐2‐(dimethylamino)‐acetate
Author(s) -
Huys Fabienne,
Merényi Robert,
Janousek Zdenek,
Stella Lucien,
Viehe Heinz Günter
Publication year - 1979
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197906151
Subject(s) - disproportionation , intramolecular force , geminal , chemistry , radical disproportionation , radical , derivative (finance) , acceptor , medicinal chemistry , substitution (logic) , photochemistry , stereochemistry , organic chemistry , catalysis , physics , computer science , financial economics , economics , programming language , condensed matter physics
Compounds having geminal capto‐dative substitutents contain a donor and an acceptor group bonded to the same C atom;such substitution stabilizes radicals. Compound (1) is an example; its remarkable Cl,H disproportionation to give the glyoxalic ester derivative (2) probably proceeds via a radical.