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Use of Biogenetic Key Compounds for the Biomimetic Synthesis of Natural Products: (S) ‐Elenolide from Secologanin
Author(s) -
Tietze LutzF,
Uzar Horst C.
Publication year - 1979
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197905391
Subject(s) - mimicry , chemistry , key (lock) , combinatorial chemistry , organic chemistry , stereochemistry , biology , ecology
Mimicry of nature has considerable advantages in the synthesis of alkaloids and similar substances; just a few reaction steps generally lead to enantiomerically pure products. The three‐step synthesis of (S) ‐elenolide (2) from secologanin (1) is an example.