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Di‐ tert ‐Butyl Acetylenedicarboxylate and Its Cyclotrimerization
Author(s) -
Sucrow Wolfgang,
Lübbe Fritz
Publication year - 1979
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197901491
Subject(s) - steric effects , cleavage (geology) , chemistry , dimethyl acetylenedicarboxylate , medicinal chemistry , acetylenedicarboxylate , base (topology) , stereochemistry , organic chemistry , catalysis , mathematics , materials science , mathematical analysis , fracture (geology) , cycloaddition , composite material
Di‐ tert —butylacetylenedicarboxylate (1) —surprisingly not synthesized before—is remarkable from a chemical standpoint. Its cyclotrimerization shows that the tert ‐butyl groups do not exert strong steric hindrance. Ready cleavage (without base) of the esters obtained from (1) is of advantage.