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Ring‐Opening of 5‐(Bromomethyl)‐2‐isoxazolines to β,γ‐Enoximes—A New Principle for the γ‐Substitution of Allyl Bromides by α‐Functionalized Alkyl Groups
Author(s) -
Jäger Volker,
Grund Hartmut,
Schwab Wilfried
Publication year - 1979
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197900781
Subject(s) - substitution (logic) , alkyl , ring (chemistry) , chemistry , medicinal chemistry , substitution reaction , sequence (biology) , organic chemistry , computer science , programming language , biochemistry
Reductive‐eliminating ring opening of isoxazolines (2) is the key step of a reaction sequence for controlled γ‐substitution of allyl bromides (1) . The reaction may give oximes (3) , ketones (4) , or their secondary products.