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Bicyclo[2.2.2]octa‐5,7‐die‐2‐one (“Barrelenone”)
Author(s) -
Gompper Rudolf,
Etzbach KarlHeinz
Publication year - 1978
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197806031
Subject(s) - bicyclic molecule , alkylation , chemistry , ion , methylation , medicinal chemistry , stereochemistry , organic chemistry , catalysis , biochemistry , gene
Barrelenon (1) , which forms an ambifunctional anion , has been synthesized in order to subject the alkylation of this anion to a comparative study. The course of methylation of the anion of (1) and the anions of other bicyclic ketones conforms with the predictions of the principle of allopolarization.