Premium
Facile Synthesis of Functionally Substituted Cyclopentenones and Butenolides from Functional Vinyl Carbanions
Author(s) -
Schmidt Richard R.,
Talbiersky Jörg
Publication year - 1978
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197802041
Subject(s) - carbanion , synthon , deprotonation , cycloaddition , chemistry , organic chemistry , catalysis , ion
A substituted C 3 synthon , the vinyl carbanion (2) , is surprisingly formed by deprotonation of the ester (1) by strong bases. Cycloaddition to (2) gives the five‐membered rings (3) and (4) , which are of significance in the synthesis of natural products.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom