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Quantitative Resolution of Enantiomers of trans ‐2,3‐Epoxybutane by Complexation Chromatography on an Optically Active Nickel( II ) Complex
Author(s) -
Schurig Volker,
Bürkle Waldemar
Publication year - 1978
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197801321
Subject(s) - enantiomer , derivatization , resolution (logic) , chemistry , optically active , nickel , chromatography , gas chromatography , organic chemistry , high performance liquid chromatography , computer science , artificial intelligence
Determination of the enantiomeric composition of chiral substrates is of considerable importance in many branches of chemistry, pharmacy, etc. 2,3‐Epoxybutane has now been quantitatively resolved into three fractions, viz. the two trans forms and the cis form. This resolution by complexation gas chromatography requires neither derivatization nor extensive purification.