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Oxepinobenzofurans—The True Nature of Sterically Hindered “Benzoxetes”
Author(s) -
Meier Herbert,
Schneider HansPeter,
Rieker Anton,
Hitchcock Peter B.
Publication year - 1978
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197801211
Subject(s) - steric effects , biogenesis , phenols , chemistry , oxidative coupling of methane , natural (archaeology) , coupling (piping) , stereochemistry , organic chemistry , biochemistry , biology , materials science , gene , paleontology , methane , metallurgy
The compounds hitherto regarded as benzoxetes (1) have proved to be oxepins (2) . Structure (3) was ruled out by X‐ray structure analysis of (2) , R 1 = t Bu, R 2 R 4 Cl, R 3 OMe. This result appears particularly important with regard to oxidative coupling of phenols (biogenesis of phenolic natural products).