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New Developments in the Field of Vitamin B 12 : Enzymatic Reactions Dependent upon Corrins and Coenzyme B 12
Author(s) -
Schrauzer G. N.
Publication year - 1977
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197702331
Subject(s) - cofactor , enzyme , vitamin b , chemistry , enzyme catalysis , biochemistry , vitamin , redox , stereochemistry , organic chemistry
Simple corrins such as vitamin B 12 and vitamin B 12 coenzyme catalyze a variety of unusual enzymatic reactions of which some are still without analogy in organic or organometallic chemistry. The mechanisms of these reactions are currently the subject of lively discussion. The present review focuses attention on new ideas about the mode of action of vitamin B 12 coenzymes in enzymatic reactions.