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Reactions of Phosgeniminium Salts with Nitriles, Imino Ethers and Imidoyl Chlorides—Synthesis of 4,6‐Dichloro‐2‐(dialkylamino)pyrimidines
Author(s) -
Stelander Bernard,
Viehe Heinz Günter
Publication year - 1977
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197701892
Subject(s) - yield (engineering) , chemistry , pyrimidine , pyrolysis , medicinal chemistry , organic chemistry , stereochemistry , materials science , metallurgy
A new pyrimidine synthesis starts from phosgeniminium salts (1) which react in the presence of HCl even with non‐activated nitriles to give the novel salts (2) . On pyrolysis, compounds (2) yield the symmetrical dichlorodialkylaminopyrimidines (3) .
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