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Synthesis of Hypericin and Related meso ‐Naphthodianthrones by Alkaline Dimerization of Hydroxyanthraquinones
Author(s) -
Rodewald Gisbert,
Arnold Rüdiger,
Griesler Johannes,
Steglich Wolfgang
Publication year - 1977
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197700462
Subject(s) - hypericin , emodin , chemistry , stereochemistry , biochemistry , pharmacology , biology
Alkaline dimerization of emodin (1a) leads to hypericin (2a) instead of isohypericin as formerly assumed. The analogous compounds (1b) and (1c) react in the same way to give (2b) and (2c).