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Nucleophilic Substitution of Vinylic Hydrogen Atoms by Carbanions
Author(s) -
Reetz Manfred T.,
Schinzer Dieter
Publication year - 1977
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197700442
Subject(s) - carbanion , elongation , chemistry , sequence (biology) , chain (unit) , nucleophilic substitution , nucleophile , hydrogen , substitution (logic) , terminal (telecommunication) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , materials science , physics , computer science , metallurgy , ultimate tensile strength , programming language , telecommunications , biochemistry , astronomy
Chain elongation of activated terminal olefins can be accomplished by the reaction sequence (1) → (2) → (3). It is also feasible with R = tert ‐butyl, cyclopropyl, and other bulky groups.