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New Developments in the Field of Vitamin B 12 : Reactions of the Cobalt Atom in Corrins and in Vitamin B 12 Model Compounds
Author(s) -
Schrauzer G. N.
Publication year - 1976
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197604171
Subject(s) - corrinoid , cobalt , vitamin b , chemistry , vitamin , cofactor , enzyme , stereochemistry , medicinal chemistry , organic chemistry , combinatorial chemistry , biochemistry , methylation , methyltransferase , gene
Studies with vitamin B 12 model compounds such as the cobaloximes provide a basis for the understanding of the mode of action of corrinoid coenzymes in enzymatic reactions. They also widen our knowledge of the properties and reactions of organocobalt compounds. The present article outlines the most important nonenzymatic reactions of cobalt in vitamin B 12 and in model compounds of the cobaloxime type.