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Oxathiazinone Dioxides—A New Group of Sweetening Agents
Author(s) -
Clauss Karl,
Jensen Harald
Publication year - 1973
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197308691
Subject(s) - sweetening , chemistry , isocyanate , alkyl , organic chemistry , group (periodic table) , medicinal chemistry , sweetening agents , food science , polyurethane
1,2,3‐0xathiazin‐4(3 H )‐one 2,2‐dioxides bearing lower alkyl substituents on C‐5 and C‐6 represent potential sweeteners. They are formed from chloro‐ or fluorosulfonyl isocyanate and acetylenes, ketones, β‐diketones, β‐oxo carboxylic esters, or benzyl vinyl ethers via N ‐halosulfonyl β‐oxo carboxamides as common intermediates.