Premium
Chemistry and Biosynthesis of the Hypothalamic Releasing and Inhibiting Neurohormones
Author(s) -
Folkers Karl,
Johansson NilsGunnar,
Hooper Fred,
Currie Bruce,
Sievertsson Hans,
Chang JawKang,
Bowers Cyril Y.
Publication year - 1973
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197302551
Subject(s) - neurohormones , hypothalamus , hormone , chemistry , endocrinology , medicine , biosynthesis , hypothalamic hormones , peptide hormone , oligopeptide , biology , pituitary hormones , biochemistry , peptide , enzyme
The hypothalamus secretes hormones which in turn affect the release of hormones from the anterior lobe of the pituitary gland. Evidence has so far been adduced for the existence of seven hypothalamic releasing hormones and three inhibiting hormones. These neurohormones are all oligopeptides and occur in only nanogram amounts in the hypothalamus. The study of synthetic analogs has provided valuable information regarding their mechanism of action.