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Methods of Asymmetric Synthesis—Enantioselective Catalytic Hydrogenation
Author(s) -
Izumi Yoshiharu
Publication year - 1971
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197108711
Subject(s) - enantioselective synthesis , raney nickel , catalysis , optically active , asymmetric hydrogenation , combinatorial chemistry , chemistry , organic chemistry , stereochemistry
It is proposed that asymmetric syntheses be divided into enantioselective and diastereoselective syntheses. The enantioselective hydrogenations discussed in the present progress report were catalyzed by Raney nickel that had previously been treated with solutions of optically active compounds. Relationships exist between the enantioselectivity of the catalyst and the structure of the chiral compound used to modify it.