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Lac Repressor
Author(s) -
MüllerHill Benno
Publication year - 1971
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197101601
Subject(s) - lac repressor , repressor , inducer , escherichia coli , lac operon , chemistry , biochemistry , biology , gene , gene expression
Repressors are proteins that interact with inducers and operators to regulate the synthesis of enzymes in the cell. Lac repressor ensures that sufficient β‐galactosidase is available to the bacterium Escherichia coli, depending upon the amount of lactose present in the culture medium. It has proved possible to isolate lac repressor from E.coli. The present progress report describes how these discoveries were made, as well as the formation and mode of action of the repressor.