Premium
Interferons
Author(s) -
Murthy Y. K. S.,
Anders HansPeter
Publication year - 1970
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.197004801
Subject(s) - interferon , nucleic acid , in vitro , in vivo , rna , biology , protein biosynthesis , virus , chemistry , virology , biochemistry , gene , microbiology and biotechnology
Interferons are proteins which bring about a nonspecific and nonimmunological defence reaction against virus infections in vertebrates. Interferon formation is induced in vivo and in vitro by viruses and other agents, e.g. endotoxins, nucleic acids, synthetic anionic copolymers, and phytohemagglutinins. All attempts to produce pure interferons have so far been unsuccessful. Interferons can only exert an antiviral action when the cellular RNA and protein synthesis is intact.