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Replacement of Plasma by High Molecular Weight Substances
Author(s) -
Appel W.,
Biekert E.
Publication year - 1968
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196807021
Subject(s) - polyvinylpyrrolidone , gelatin , hydroxyethyl starch , dextran , natural polymers , polymer , chemistry , starch , plasma , polymer chemistry , chromatography , organic chemistry , biochemistry , physics , quantum mechanics
Abstract In the course of the development work, natural and synthetic polymers were examined to see whether they were suitable for use as plasma substitutes. The criteria of a plasma substitute are discussed in this connection. The most important of the base substances used at present (dextran, modified gelatin, polyvinylpyrrolidone, and hydroxyethyl starch) are described, and a typical example of proven therapeutic value is discussed for each type.