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Spatial Arrangement and Preparative Organic Synthesis
Author(s) -
Velluz L.,
Valls J.,
Mathieu J.
Publication year - 1967
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196707781
Subject(s) - stereoselectivity , resolution (logic) , organic synthesis , chemistry , combinatorial chemistry , organic chemistry , computer science , artificial intelligence , catalysis
This review deals with the stereoselective formation of organic compounds. A number of examples of such syntheses, especially those of alkaloids and steroids, are described. An asymmetric synthesis, which avoids the intricacies and wastefulness of optical resolution, has been successful in a few cases only. The procedures of configurational change and of optical resolution, as well as the planning of multi‐step stereoselective syntheses, are discussed.