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Additions to the Activated CC Triple Bond
Author(s) -
Winterfeldt E.
Publication year - 1967
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196704231
Subject(s) - triple bond , thiophene , pyrrole , chemistry , primary (astronomy) , combinatorial chemistry , bond , hydrogen bond , medicinal chemistry , computational chemistry , organic chemistry , double bond , business , molecule , physics , finance , astronomy
Abstract The possibilities of additions to the activated CC triple bond are discussed with the aid of a number of examples. The additions of donors that contain no active hydrogen are generally initiated via a dipolar primary complex, which can undergo stabilization by rearrangement, cyclization, or addition reactions. Preparative aspects of these reactions are also discussed. They offer routes for the preparation of heterocycles, particularly pyrrole and thiophene derivatives.