Premium
The Prostaglandins
Author(s) -
Samuelsson B.
Publication year - 1965
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196504101
Subject(s) - chemistry , double bond , metabolism , ring (chemistry) , mass spectrometry , stereochemistry , gas chromatography , biochemistry , organic chemistry , chromatography
Prostaglandins occur in many animal species and tissues. They are C 20 ‐carboxylic acids contining one five‐membered ring, one keto group, two or three hydroxy groups, and one to three CC double bonds. Their structures were elucidated by chemical, radiochemical, and physical methods in combination with gas chromatography and mass spectrometry. The prostaglandins are biosynthesized from essential fatty acids. By their action smooth muscles are stimulated and lipid metabolism is affected.