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New Methods in the Chemistry Pyridazones
Author(s) -
Dury K.
Publication year - 1965
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196502921
Subject(s) - reactivity (psychology) , chemistry , chlorine , condensation , chlorine atom , organic chemistry , combinatorial chemistry , condensation reaction , medicinal chemistry , catalysis , medicine , physics , alternative medicine , pathology , thermodynamics
A new synthesis of mucochloric acid by chlorination of butynediol has facilitated the preparation of a series of 4,5‐dichoropyridazones. The high reactivity of these compounds has been investigated and applied in several ways. New classes of compounds, some with biological activity, were obtained by displacement of the chlorine atoms. New heterocyclic systems were prepared by condensation and rearrangement reactions.