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Preparative and Analytical Separation of Organic Compounds by Means of Chromatography on Polyamide
Author(s) -
Endres Horst,
Hörmann Helmut
Publication year - 1963
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196302541
Subject(s) - polyamide , chemistry , phenols , organic chemistry , nitro , chromatography , polymer , alkyl
Columns of polyamide are well suited for chromatographic separation of numerous organic compounds, especially phenols, carboxylic acids, and aromatic nitro compounds. The method is also useful for isolating naturally occurring compounds on a preparative scale. The affinity of phenols for polyamides is due to the formation of hydrogen bonds to the peptide linkages of the polyamide, while aromatic nitro compounds are retained by means of free amino groups in the polymer. Quinones react irreversibly with the free amino groups of the polyamide. Quinones are not retained by acetylated polyamides although phenols are.