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Nucleotide Intermediates in the Biosynthesis of Polysaccharides
Author(s) -
Strominger Jack L.
Publication year - 1962
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.196201341
Subject(s) - nucleotide , biosynthesis , biochemistry , nucleic acid , polysaccharide , chemistry , metabolism , gene
Abstract In metabolism, nucleotides play a roLe not only as the procursors of nucleic acids. Many low molecular weight compounds may be activated for subsequent biosysthesis by forming anhydrides or esters with nucletides. These nucleotide derivatives functions as carriers of the residues attached to them. Frequently the residues become chemically changed while a attched to the nucleotide before transfer in a biosynthetic reaction. Following a general survey of nucleotide‐types, and their reaction, into the biosynthesis of sulfated polysaccharides is described.