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Metal‐Organic Frameworks for Practical Separation of Cyclic and Linear Polymers
Author(s) -
Sawayama Taku,
Wang Yubo,
Watanabe Tomohisa,
Takayanagi Masayoshi,
Yamamoto Takuya,
Hosono Nobuhiko,
Uemura Takashi
Publication year - 2021
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202102794
Subject(s) - polymer , adsorption , metal organic framework , linear polymer , fractionation , chemistry , impurity , separation method , chromatographic separation , metal , chemical engineering , materials science , chromatography , organic chemistry , high performance liquid chromatography , engineering
The purification step in the manufacturing of cyclic polymers is difficult as complete fractionation to eliminate linear impurities requires considerable effort. Here, we report a new polymer separation methodology that uses metal‐organic frameworks (MOFs) to discriminate between linear and cyclic polyethylene glycols (PEGs) via selective polymer insertion into the MOF nanopores. Preparation of a MOF‐packed column allowed analytical and preparative chromatographic separation of these topologically distinct pairs. In addition, gram‐scale PEGs with only cyclic structures were successfully obtained from a crude reaction mixture by using MOF as an adsorbent.