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Single‐Stranded DNA as Supramolecular Template for One‐Dimensional Palladium(II) Arrays
Author(s) -
PérezRomero Antonio,
DomínguezMartín Alicia,
Galli Simona,
SantamaríaDíaz Noelia,
Palacios Oscar,
Dobado José A.,
Nyman May,
Galindo Miguel A.
Publication year - 2021
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202015554
Subject(s) - supramolecular chemistry , chemistry , crystallography , small angle x ray scattering , palladium , dna , molecule , nucleobase , base pair , ab initio , dna origami , scattering , crystal structure , physics , catalysis , organic chemistry , biochemistry , optics
Atomic‐level control over the position and growth of a single and continuous metal chain is an ambitious goal that often requires complex and costly processes. Herein, we demonstrate that 1Pd‐DNA molecules, comprising a continuous single chain of Pd II ions, can be prepared by a simple self‐assembly reaction between the complex [Pd(Cheld)(CH 3 CN)] ( 1Pd_CH 3 CN ) (Cheld=chelidamic acid) and single‐stranded DNA homopolymers (ss‐DNA) containing adenine ( A ) or 7‐deazaadenine ( X ) bases. The single Pd II ‐base pairs [1Pd(N1‐A)] and [1Pd(N1‐X)] were synthesized and characterized in solution and solid‐state (X‐ray diffraction) revealing an arrangement similar to that of natural Watson–Crick base pairs. Subsequently, 1Pd‐DNA hybrids were prepared, characterized, and their structures studied by small‐angle X‐ray scattering (SAXS) and ab‐initio calculations. The results indicate that the 1Pd‐DNA structures resemble that of double‐stranded DNA, with one strand being replaced by a supramolecular stack of continuous Pd II complexes.