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Interfacial Microcompartmentalization by Kinetic Control of Selective Interfacial Accumulation
Author(s) -
Liu Qian,
Yuan Zhenyu,
Zhao Meng,
Huisman Max,
Drewes Gido,
Piskorz Tomasz,
Mytnyk Serhii,
Koper Ger J. M.,
Mendes Eduardo,
Esch Jan H.
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202009701
Subject(s) - polymer , polyethylene glycol , chemical engineering , aqueous solution , phase (matter) , materials science , pulmonary surfactant , aqueous two phase system , peg ratio , layer (electronics) , emulsion , polymer chemistry , chemistry , nanotechnology , organic chemistry , composite material , finance , engineering , economics
Reported here is a 2D, interfacial microcompartmentalization strategy governed by 3D phase separation. In aqueous polyethylene glycol (PEG) solutions doped with biotinylated polymers, the polymers spontaneously accumulate in the interfacial layer between the oil‐surfactant‐water interface and the adjacent polymer phase. In aqueous two‐phase systems, these polymers first accumulated in the interfacial layer separating two polymer solutions and then selectively migrated to the oil‐PEG interfacial layer. By using polymers with varying photopolymerizable groups and crosslinking rates, kinetic control and capture of spatial organisation in a variety of compartmentalized macroscopic structures, without the need of creating barrier layers, was achieved. This selective interfacial accumulation provides an extension of 3D phase separation towards synthetic compartmentalization, and is also relevant for understanding intracellular organisation.