A Next‐Generation Air‐Stable Palladium(I) Dimer Enables Olefin Migration and Selective C−C Coupling in Air | Zendy

Kundu Gourab | Zendy; Sperger Theresa | Zendy; Rissanen Kari | Zendy; Schoenebeck Franziska | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Next‐Generation Air‐Stable Palladium(I) Dimer Enables Olefin Migration and Selective C−C Coupling in Air

Author(s) -

Kundu Gourab,

Sperger Theresa,

Rissanen Kari,

Schoenebeck Franziska

Publication year - 2020

Publication title -

angewandte chemie

Language(s) - English

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.202009115

Subject(s) - dimer , olefin fiber , palladium , chemistry , alkylation , styrene , coupling (piping) , stereochemistry , medicinal chemistry , organic chemistry , catalysis , materials science , polymer , copolymer , metallurgy

We report a new air‐stable Pd I dimer, [Pd(μ‐I)(PCy 2 t Bu)] 2 , which triggers E ‐selective olefin migration to enamides and styrene derivatives in the presence of multiple functional groups and with complete tolerance of air. The same dimer also triggers extremely rapid C−C coupling (alkylation and arylation) at room temperature in a modular and triply selective fashion of aromatic C−Br, C−OTf/OFs, and C−Cl bonds in poly(pseudo)halogenated arenes, displaying superior activity over previous Pd I dimer generations for substrates that bear substituents ortho to C−OTf.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research