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Direct and Selective Synthesis of Adipic and Other Dicarboxylic Acids by Palladium‐Catalyzed Carbonylation of Allylic Alcohols
Author(s) -
Yang Ji,
Liu Jiawang,
Ge Yao,
Huang Weiheng,
Neumann Helfried,
Jackstell Ralf,
Beller Matthias
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202008916
Subject(s) - carbonylation , palladium , allylic rearrangement , chemistry , catalysis , adipic acid , selectivity , ligand (biochemistry) , alcohol , organic chemistry , dicarboxylic acid , combinatorial chemistry , carbon monoxide , receptor , biochemistry
A general and direct synthesis of dicarboxylic acids including industrially important adipic acid by palladium‐catalyzed dicarbonylation of allylic alcohol is reported. Specifically, the combination of PdCl 2 and a bisphosphine ligand (HeMaRaphos) promotes two different carbonylation reactions with high activity and excellent selectivity.