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Using the Secondary PH/BH Functional Groups of an Active Geminal Frustrated Lewis Pair for Carbon Monoxide Reduction and Reactions with Nitriles and Isonitriles
Author(s) -
Li Jun,
MückLichtenfeld Christian,
Daniliuc Constantin G.,
Kehr Gerald,
Erker Gerhard
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202000612
Subject(s) - chemistry , geminal , frustrated lewis pair , benzonitrile , cycloaddition , carbon monoxide , medicinal chemistry , lewis acids and bases , chemoselectivity , organic chemistry , stereochemistry , catalysis
Reaction of the secondary alkynyl(Mes*)PH phosphane 2 with (Fmes)BH 2 ⋅SMe 2 gives the geminal PH/BH frustrated Lewis pair (FLP) 3 . The PH and the BH functions are jointly used in the reduction of carbon monoxide under mild reaction conditions to give the [P]‐CH 2 ‐O‐[B] product. A subsequent cycloaddition sequence results in the liberation of formaldehyde. The FLP 3 reacts with benzonitrile to give a P‐benzamidine, and it couples two isonitriles at the FLP framework.