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Preparative Mass Spectrometry Using a Rotating‐Wall Mass Analyzer
Author(s) -
Su Pei,
Hu Hang,
Unsihuay Daisy,
Zhang Di,
Dainese Tiziano,
Diaz Rosa E.,
Lee Jongsu,
Gunaratne Don K.,
Wang Haiyan,
Maran Flavio,
Mei Jianguo,
Laskin Julia
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.202000065
Subject(s) - mass spectrometry , ion , characterization (materials science) , deposition (geology) , molecule , nanotechnology , chemistry , analytical chemistry (journal) , chemical physics , nanocrystal , polyatomic ion , materials science , chromatography , organic chemistry , paleontology , sediment , biology
The design of functional interfaces is central to both fundamental and applied research in materials science and energy technology. We introduce a new, broadly applicable technique for the precisely controlled high‐throughput preparation of well‐defined interfaces containing polyatomic species ranging from small ions to nanocrystals and large protein complexes. The mass‐dispersive deposition of ions onto surfaces is achieved using a rotating‐wall mass analyzer, a compact device which enables the separation of ions using low voltages and has a theoretically unlimited mass range. We demonstrate an efficient deposition of singly charged Au 144 (SC 4 H 9 ) 60 ions (33.7 kDa), which opens up exciting opportunities for the structural characterization of nanocrystals and their assemblies using transmission electron microscopy. Our approach also enables the high‐throughput deposition of mass‐selected ions from multicomponent mixtures, which is of interest to the controlled preparation of surface gradients and rapid screening of molecules in mixtures for a specific property.