Premium
Stereoselective Base‐Catalyzed 1,1‐Silaboration of Terminal Alkynes
Author(s) -
Gu Yiting,
Duan Yaya,
Shen Yangyang,
Martin Ruben
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201913544
Subject(s) - stereoselectivity , geminal , catalysis , chemistry , combinatorial chemistry , terminal (telecommunication) , base (topology) , atom (system on chip) , stereochemistry , organic chemistry , computer science , mathematics , embedded system , telecommunications , mathematical analysis
A base‐catalyzed reaction that enables stereoselective 1,1‐silaboration of terminal alkynes is described. This method not only offers a new strategy to functionalize simple and readily accessible alkynes beyond 1,2‐difunctionalization, but also provides an unconventional atom‐ and step‐economical approach to rapidly and reliably access versatile geminal silylboranes in the absence of transition metals and with exquisite stereoselectivity.