Premium
Naked‐Eye Readout of Analyte‐Induced NIR Fluorescence Responses by an Initiation–Input–Transduction Nanoplatform
Author(s) -
Zhang Dailiang,
Wang Linlin,
Yuan Xi,
Gong Yijun,
Liu Hongwen,
Zhang Jing,
Zhang Xiaobing,
Liu Yanlan,
Tan Weihong
Publication year - 2020
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201911113
Subject(s) - naked eye , analyte , fluorophore , fluorescence , transducer , near infrared spectroscopy , transduction (biophysics) , luminescence , nanotechnology , materials science , chemistry , luminescent measurements , optoelectronics , optics , biochemistry , physics , quantum mechanics
Fluorescence visualization (FV) in the near‐infrared (NIR) window promises to break through the signal‐to‐background ratio (SBR) bottleneck of traditional visible‐light‐driven FV methods. However, straightforward NIR‐FV has not been realized, owing to the lack of methods to readily transduce NIR responses into instrument‐free, naked eye‐recognizable outputs. Now, an initiation–input–transduction platform comprising a well‐designed NIR fluorophore as the signal initiator and lanthanide‐doped nanocrystals as the transducer for facile NIR‐FV is presented. The analyte‐induced off–on NIR signal serves as a sensitizing switch of transducer visible luminescence for naked‐eye readout. The design is demonstrated for portable, quantitative detection of phosgene with significantly improved SBR and sensitivity. By further exploration of initiators, this strategy holds promise to create advanced NIR‐FV probes for broad sensing applications.