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Ligand‐Promoted Iron(III)‐Catalyzed Hydrofluorination of Alkenes
Author(s) -
Xie Yongtao,
Sun PengWei,
Li Yuxin,
Wang Siwei,
Ye Mengchun,
Li Zhengming
Publication year - 2019
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201902607
Subject(s) - reagent , chemistry , ligand (biochemistry) , denticity , yield (engineering) , catalysis , combinatorial chemistry , halogenation , organic chemistry , crystal structure , materials science , biochemistry , receptor , metallurgy
An iron‐catalyzed hydrofluorination of unactivated alkenes has been developed. The use of a multidentate ligand and the fluorination reagent N ‐fluorobenzenesulfonimide (NFSI) proved to be critical for this reaction, which afforded various fluorinated compounds in up to 94 % yield.