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Photoelectrochemical C−H Alkylation of Heteroarenes with Organotrifluoroborates
Author(s) -
Yan Hong,
Hou ZhongWei,
Xu HaiChao
Publication year - 2019
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201814488
Subject(s) - alkylation , chemistry , photoredox catalysis , chemoselectivity , electrocatalyst , catalysis , primary (astronomy) , surface modification , alkyl , radical , combinatorial chemistry , organic chemistry , electrochemistry , photocatalysis , electrode , physics , astronomy
A photoelectrochemical method for the C−H alkylation of heteroarenes with organotrifluoroborates has been developed. The merger of electrocatalysis and photoredox catalysis provides a chemical oxidant‐free approach for the generation and functionalization of alkyl radicals from organotrifluoroborates. A variety of heteroarenes were functionalized using primary, secondary, and tertiary alkyltrifluoroborates with excellent regio‐ and chemoselectivity.