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Substrate‐Induced Self‐Assembly of Cooperative Catalysts
Author(s) -
Solís Muñana Pablo,
Ragazzon Giulio,
Dupont Julien,
Ren Chloe Z.J.,
Prins Leonard J.,
Chen Jack L.Y.
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201810891
Subject(s) - chemistry , substrate (aquarium) , catalysis , cleavage (geology) , substrate specificity , dissipative system , nanotechnology , combinatorial chemistry , biophysics , chemical engineering , materials science , biochemistry , physics , enzyme , engineering , oceanography , quantum mechanics , fracture (geology) , composite material , geology , biology
Dissipative self‐assembly processes in nature rely on chemical fuels that activate proteins for assembly through the formation of a noncovalent complex. The catalytic activity of the assemblies causes fuel degradation, resulting in the formation of an assembly in a high‐energy, out‐of‐equilibrium state. Herein, we apply this concept to a synthetic system and demonstrate that a substrate can induce the formation of vesicular assemblies, which act as cooperative catalysts for cleavage of the same substrate.