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Iridium‐Catalyzed Electrooxidative C−H Activation by Chemoselective Redox‐Catalyst Cooperation
Author(s) -
Qiu Youai,
Stangier Maximilian,
Meyer Tjark H.,
Oliveira João C. A.,
Ackermann Lutz
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201809611
Subject(s) - iridium , chemistry , catalysis , redox , electrochemistry , electrolysis , platinum , photochemistry , bulk electrolysis , inorganic chemistry , combinatorial chemistry , cyclic voltammetry , organic chemistry , electrode , electrolyte
Iridium‐catalyzed electrochemical C−H activation was accomplished within a cooperative catalysis manifold, setting the stage for electrooxidative C−H alkenylations through weak O‐coordination. The iridium‐electrocatalyzed C−H activation featured high functional‐group tolerance through assistance of a metal‐free redox mediator through indirect electrolysis. Detailed mechanistic insights provided strong support for an organometallic C−H cleavage and a synergistic iridium(III/I)/redox catalyst regime, enabling the use of sustainable electricity as the terminal oxidant with improved selectivity features.