Premium
Gold(I)‐Catalyzed Tandem Cycloisomerization of 1,5‐Enyne Ethers by Hydride Transfer
Author(s) -
Lu XiaoLin,
Lyu MaoYun,
Peng XiaoShui,
Wong Henry N. C.
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201806842
Subject(s) - cycloisomerization , tandem , chemistry , catalysis , hydride , enyne , stereospecificity , ring (chemistry) , cascade reaction , combinatorial chemistry , photochemistry , stereochemistry , organic chemistry , metal , materials science , composite material
A novel gold‐catalyzed tandem protocol, initiated by hydride transfer in the presence of catalytic (C 6 F 5 ) 3 PAuCl/AgSbF 6 , for the formation of fused polycyclic ring systems has been achieved. This tandem reaction provides rapid access to various fused polycyclic species in a single chemical operation, leading to stereospecific formation of two carbon–carbon bonds and three rings.