Direct Cross‐Coupling of Allylic C(sp 3 )−H Bonds with Aryl‐ and Vinylbromides by Combined Nickel and Visible‐Light Catalysis | Zendy

Huang Long | Zendy; Rueping Magnus | Zendy

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Direct Cross‐Coupling of Allylic C(sp 3 )−H Bonds with Aryl‐ and Vinylbromides by Combined Nickel and Visible‐Light Catalysis

Author(s) -

Huang Long,

Rueping Magnus

Publication year - 2018

Publication title -

angewandte chemie

Language(s) - English

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.201805118

Subject(s) - allylic rearrangement , regioselectivity , aryl , catalysis , nickel , chemistry , photocatalysis , functional group , surface modification , visible spectrum , coupling reaction , photochemistry , combinatorial chemistry , medicinal chemistry , materials science , organic chemistry , alkyl , optoelectronics , polymer

An efficient protocol for the direct allylic C(sp 3 )−H bond activation of unactivated tri‐ and tetrasubstituted alkenes and their functionalization with aryl‐ and vinylbromides by nickel and visible‐light photocatalysis has been developed. The method allows C(sp 2 )−C(sp 3 ) formation under mild reaction conditions with good functional‐group tolerance and excellent regioselectivity.

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