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Manganese‐Catalyzed Direct Olefination of Methyl‐Substituted Heteroarenes with Primary Alcohols
Author(s) -
Barman Milan K.,
Waiba Satyadeep,
Maji Biplab
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201804729
Subject(s) - primary (astronomy) , catalysis , manganese , chemistry , ligand (biochemistry) , pincer movement , pincer ligand , combinatorial chemistry , transition metal , organic chemistry , biochemistry , physics , receptor , astronomy
Herein, we present the first catalytic direct olefination of methyl‐substituted heteroarenes with primary alcohols through an acceptorless dehydrogenative coupling. The reaction is catalyzed by a complex of the earth‐abundant transition metal manganese that is stabilized by a bench‐stable NNN pincer ligand derived from 2‐hydrazinylpyridine. The reaction is environmentally benign, producing only hydrogen and water as byproducts. A large number of E ‐disubstituted olefins were selectively obtained with high efficiency.