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Regioselective Cyclotrimerization of Terminal Alkynes Using a Digermyne
Author(s) -
Sugahara Tomohiro,
Guo JingDong,
Sasamori Takahiro,
Nagase Shigeru,
Tokitoh Norihiro
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201801222
Subject(s) - regioselectivity , chemistry , bespoke , terminal (telecommunication) , molecule , catalysis , stereochemistry , combinatorial chemistry , organic chemistry , computer science , telecommunications , political science , law
The catalytic activation of small neutral molecules followed by the formation of C−C bonds is a highly important method to increase the complexity and/or value of simple starting materials. Reported is an isolable digermyne, a compound with a Ge≡Ge bond, which acts as a precatalyst for the cyclotrimerization of terminal arylacetylenes to afford the corresponding 1,2,4‐triarylbenzenes with absolute regioselectivity. The results demonstrate that bespoke main‐group‐element compounds can catalytically activate and transform small neutral organic molecules and induce the formation of C−C bonds.