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Nanoisozymes: Crystal‐Facet‐Dependent Enzyme‐Mimetic Activity of V 2 O 5 Nanomaterials
Author(s) -
Ghosh Sourav,
Roy Punarbasu,
Karmodak Naiwrit,
Jemmis Eluvathingal D.,
Mugesh Govindasamy
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201800681
Subject(s) - nanomaterials , redox , hydrogen peroxide , facet (psychology) , chemistry , nanotechnology , crystal (programming language) , peroxidase , enzyme , materials science , inorganic chemistry , biochemistry , social psychology , psychology , personality , computer science , big five personality traits , programming language
Nanomaterials with enzyme‐like activity (nanozymes) attract significant interest owing to their applications in biomedical research. Particularly, redox nanozymes that exhibit glutathione peroxidase (GPx)‐like activity play important roles in cellular signaling by controlling the hydrogen peroxide (H 2 O 2 ) level. Herein we report, for the first time, that the redox properties and GPx‐like activity of V 2 O 5 nanozyme depends not only on the size and morphology, but also on the crystal facets exposed on the surface within the same crystal system of the nanomaterials. These results suggest that the surface of the nanomaterials can be engineered to fine‐tune their redox properties to act as “nanoisozymes” for specific biological applications.