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Electrochemical Oxidative C−H Amination of Phenols: Access to Triarylamine Derivatives
Author(s) -
Tang Shan,
Wang Siyuan,
Liu Yichang,
Cong Hengjiang,
Lei Aiwen
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201800240
Subject(s) - amination , dehydrogenation , chemistry , atom economy , electrolysis , electrochemistry , phenols , catalysis , oxidative phosphorylation , combinatorial chemistry , organic chemistry , electrolyte , electrode , biochemistry
Dehydrogenative C−H/N−H cross‐coupling serves as one of the most straightforward and atom‐economical approaches for C−N bond formation. In this work, an electrochemical reaction protocol has been developed for the oxidative C−H amination of unprotected phenols under undivided electrolytic conditions. Neither metal catalysts nor chemical oxidants are needed to facilitate the dehydrogenation process. A series of triarylamine derivatives could be obtained with good functional‐group tolerance. The electrolysis is scalable and can be performed at ambient conditions.