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Heteroleptic Copper(I)‐Based Complexes for Photocatalysis: Combinatorial Assembly, Discovery, and Optimization
Author(s) -
Minozzi Clémentine,
Caron Antoine,
GrenierPetel JeanChristophe,
Santandrea Jeffrey,
Collins Shawn K.
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201800144
Subject(s) - copper , modularity (biology) , photocatalysis , catalysis , chemistry , combinatorial chemistry , binap , enantioselective synthesis , organic chemistry , genetics , biology
A library of 50 copper‐based complexes derived from bisphosphines and diamines was prepared and evaluated in three mechanistically distinct photocatalytic reactions. In all cases, a copper‐based catalyst was identified to afford high yields, where new heteroleptic complexes derived from the bisphosphine BINAP displayed high efficiency across all reaction types. Importantly, the evaluation of the library of copper complexes revealed that even when photophysical data is available, it is not always possible to predict which catalyst structure will be efficient or inefficient in a given process, emphasizing the advantages for catalyst structures with high modularity and structural variability.